TY - JOUR
T1 - Complete sequence of a F33: A-: B- conjugative plasmid carrying the oqxAB, fosA3, and blaCTX-M-55 elements from a Foodborne Escherichia coli strain
AU - Wong, Marcus H.
AU - Xie, Miaomiao
AU - Xie, Liqi
AU - Lin, Dachuan
AU - Li, Ruichao
AU - Zhou, Yuanjie
AU - Chan, Edward W.
AU - Chen, Sheng
PY - 2016/10/27
Y1 - 2016/10/27
N2 - � 2016 Wong, Xie, Xie, Lin, Li, Zhou, Chan and Chen. This study reports the complete sequence of pE80, a conjugative IncFII plasmid recovered from an Escherichia coli strain isolated from chicken meat. This plasmid harbors multiple resistance determinants including oqxAB, fosA3, blaCTX-M-55, and blaTEM-1, and is a close variant of the recently reported p42-2 element, which was recovered from E. coli of veterinary source. Recovery of pE80 constitutes evidence that evolution or genetic re-arrangement of IncFII type plasmids residing in animal-borne organisms is an active event, which involves acquisition and integration of foreign resistance elements into the plasmid backbone. Dissemination of these plasmids may further compromise the effectiveness of current antimicrobial strategies.
AB - � 2016 Wong, Xie, Xie, Lin, Li, Zhou, Chan and Chen. This study reports the complete sequence of pE80, a conjugative IncFII plasmid recovered from an Escherichia coli strain isolated from chicken meat. This plasmid harbors multiple resistance determinants including oqxAB, fosA3, blaCTX-M-55, and blaTEM-1, and is a close variant of the recently reported p42-2 element, which was recovered from E. coli of veterinary source. Recovery of pE80 constitutes evidence that evolution or genetic re-arrangement of IncFII type plasmids residing in animal-borne organisms is an active event, which involves acquisition and integration of foreign resistance elements into the plasmid backbone. Dissemination of these plasmids may further compromise the effectiveness of current antimicrobial strategies.
KW - Dissemination
KW - E. coli
KW - FosA3
KW - IncFII plasmids
KW - OqxAB
UR - http://www.scopus.com/inward/record.url?scp=84997525070&partnerID=8YFLogxK
U2 - 10.3389/fmicb.2016.01729
DO - 10.3389/fmicb.2016.01729
M3 - Journal article
SN - 1664-302X
VL - 7
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
IS - OCT
M1 - 1729
ER -