Complete sequence of a F33: A-: B- conjugative plasmid carrying the oqxAB, fosA3, and blaCTX-M-55 elements from a Foodborne Escherichia coli strain

Marcus H. Wong, Miaomiao Xie, Liqi Xie, Dachuan Lin, Ruichao Li, Yuanjie Zhou, Edward W. Chan, Sheng Chen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

6 Citations (Scopus)

Abstract

� 2016 Wong, Xie, Xie, Lin, Li, Zhou, Chan and Chen. This study reports the complete sequence of pE80, a conjugative IncFII plasmid recovered from an Escherichia coli strain isolated from chicken meat. This plasmid harbors multiple resistance determinants including oqxAB, fosA3, blaCTX-M-55, and blaTEM-1, and is a close variant of the recently reported p42-2 element, which was recovered from E. coli of veterinary source. Recovery of pE80 constitutes evidence that evolution or genetic re-arrangement of IncFII type plasmids residing in animal-borne organisms is an active event, which involves acquisition and integration of foreign resistance elements into the plasmid backbone. Dissemination of these plasmids may further compromise the effectiveness of current antimicrobial strategies.
Original languageEnglish
Article number1729
JournalFrontiers in Microbiology
Volume7
Issue numberOCT
DOIs
Publication statusPublished - 27 Oct 2016

Keywords

  • Dissemination
  • E. coli
  • FosA3
  • IncFII plasmids
  • OqxAB

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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