Complete nucleotide sequence of a conjugative plasmid carrying blaPER-1

Ruichao Li; Marcus Ho Yin Wong; Yuanjie Zhou; Edward Wai Chi Chan; Sheng Chen

doi:10.1128/AAC.00518-15

Complete nucleotide sequence of a conjugative plasmid carrying bla_PER-1

Ruichao Li
, Marcus Ho Yin Wong
, Yuanjie Zhou
, Edward Wai Chi Chan
, Sheng Chen

Research output: Journal article publication › Journal article › Academic research › peer-review

17 Citations (Scopus)

Abstract

The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1(ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.

Original language	English
Pages (from-to)	3582-3584
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	59
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00518-15
Publication status	Published - 1 Jan 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

More information

10.1128/AAC.00518-15

Cite this

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title = "Complete nucleotide sequence of a conjugative plasmid carrying blaPER-1",

abstract = "The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1(ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.",

author = "Ruichao Li and Wong, \{Marcus Ho Yin\} and Yuanjie Zhou and Chan, \{Edward Wai Chi\} and Sheng Chen",

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T1 - Complete nucleotide sequence of a conjugative plasmid carrying blaPER-1

AU - Li, Ruichao

AU - Wong, Marcus Ho Yin

AU - Zhou, Yuanjie

AU - Chan, Edward Wai Chi

AU - Chen, Sheng

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1(ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.

AB - The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1(ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.

UR - https://www.scopus.com/pages/publications/84982156010

U2 - 10.1128/AAC.00518-15

DO - 10.1128/AAC.00518-15

M3 - Journal article

C2 - 25779581

SN - 0066-4804

VL - 59

SP - 3582

EP - 3584

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 6

ER -