Complete nucleotide sequence of a conjugative plasmid carrying blaPER-1

Ruichao Li, Marcus Ho Yin Wong, Yuanjie Zhou, Edward Wai Chi Chan, Sheng Chen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

10 Citations (Scopus)


The nucleotide sequence of a self-transmissible plasmid pVPH1 harboring blaPER-1from Vibrio parahaemolyticus was determined. pVPH1 was 183,730 bp in size and shared a backbone similar to pAQU1 and pAQU2, differing mainly in an ∼40-kb multidrug resistance (MDR) region. A complex class 1 integron was identified together with ISCR1 and blaPER-1(ISCR1-blaPER-1-gstabct-qacEΔ1-sul1), which was shown to form a circular intermediate playing an important role in the dissemination of blaPER-1.
Original languageEnglish
Pages (from-to)3582-3584
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Issue number6
Publication statusPublished - 1 Jan 2015

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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