Comparing the multifocal electroretinogram topography before and after cataract surgery

Wing Kin Tam, Ho Lung Henry Chan, Brian Brown, Kam Wah Leung, Victor Woo, Keng Hung Maurice Yap

Research output: Journal article publicationJournal articleAcademic researchpeer-review

9 Citations (Scopus)


Purpose: To investigate whether multifocal electroretinogram (mfERG) topography would be affected by nuclear cataract. Methods: Multifocal electroretinograms were recorded from 10 elderly subjects (10 eyes) with nuclear cataract of grade five (LOGS III) before and after cataract surgery (phacoemulsification). Their visual acuity before the cataract surgery was between 6/12 and 6/18. The postoperative period was from 2 to 3 months. None of the subjects had any significant eye disease apart from cataract. The mfERG responses were grouped into six concentric rings for analysis. Both the amplitudes and the latencies of N1 and P1 of first-order responses were used for analysis. Results: N1 amplitude only from ring 1 increased significantly after cataract surgery. P1 amplitude from ring 1 and ring 2 also increased significantly after cataract surgery. The latencies of neither N1 nor P1 from all rings changed significantly. Conclusions: Nuclear cataract could affect the topography of mfERG, so clinicians should be aware of the effects of cataract when interpreting mfERG responses in cataract patients.
Original languageEnglish
Pages (from-to)593-599
Number of pages7
JournalCurrent Eye Research
Issue number7
Publication statusPublished - 1 Jul 2005


  • Aging
  • Cataract
  • Intraocular lens
  • Light scattering
  • mfERG

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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