CMOS modulated light cameras for sensitive surface plasmon resonance imaging

Nicholas S. Johnston, Roger A. Light, Ciaran E. Stewart, Michael Geoffrey Somekh, Mark C. Pitter

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

1 Citation (Scopus)


Complementary metal oxide semiconductor (CMOS) cameras that can measure the phase and amplitude of periodically modulated optical signals have been developed. These allow parallel lock-in imaging at up to 256 x 256 pixels resolution without the need for slow and costly mechanical scanning. In conjunction with a differential surface plasmon resonance (dSPR) system, spatially resolved SPR imaging has been achieved with sensitivities of better than 10 microRIU per pixel per second. Results demonstrating the performance of modulated light cameras for dSPR imaging and high resolution SPR microscopy are presented and discussed.
Original languageEnglish
Title of host publicationPlasmonics in Biology and Medicine VII
Publication statusPublished - 3 May 2010
Externally publishedYes
EventPlasmonics in Biology and Medicine VII - San Francisco, CA, United States
Duration: 25 Jan 201028 Jan 2010


ConferencePlasmonics in Biology and Medicine VII
Country/TerritoryUnited States
CitySan Francisco, CA


  • CMOS cameras
  • Modulated light
  • Surface plasmon resonance imaging
  • Synchronous detection

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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