Chemical information of Chinese medicines: A challenge to chemist

Kam Wah Mok, Foo T. Chau

Research output: Journal article publicationJournal articleAcademic researchpeer-review

140 Citations (Scopus)


Fingerprint is a broad term. Different approaches are employed in developing fingerprints to characterize systems with complicated compositions. In this review, these approaches are grouped as "component based approaches" and "all-information based approaches" according to nature of the information used. Comments and discussions are given on the "component based approaches" including the commonly used "marker approach" and the "multi-component approach" as well as the "pattern approach" and the "multi-pattern approach" as categorized under "all-information based approaches". The pattern approach is embraced in China and establishment of fingerprint of Traditional Chinese Medicine (TCM) herbs and preparations is currently undergoing. A brief review of current activities is given. Several chemometrics techniques mainly developed by us and our collaborators are described. They have been applied in developing the TCM fingerprint with very good results. These demonstrated the power of these techniques, especially when coupled with hyphenated instrument, in retrieving useful chemical information from huge amount of data generated experimentally.
Original languageEnglish
Pages (from-to)210-217
Number of pages8
JournalChemometrics and Intelligent Laboratory Systems
Issue number1-2 SPEC. ISS
Publication statusPublished - 26 May 2006


  • Chemometrics
  • Fingerprint
  • Fingerprint techniques
  • Herbal medicine
  • Quality control
  • Traditional Chinese medicine

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Statistics and Probability


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