Characterization of a Microchip Device for Cell Patterning via Negative Dielectrophoresis

Kaicheng Huang, Henry K. Chu, Bo Lu, Li Cheng

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

5 Citations (Scopus)

Abstract

Patterning cells on a substrate is useful for cell assay and characterization. In this paper, a microchip employing negative dielectrophoresis was designed for efficient cell pattering. This chip consists of a 4-by-4 dot electrode array and the cell patterns are formed on a substrate lying on the microchip. To facilitate the microchip design, electric fields generated from the microchip were first simulated using software, and experiments were conducted to validate the performance of the microchip. Yeast cells suspending in the 6-aminohexanoic acid (AHA) solution were used in this study, and the effects of the cell medium, the voltage input and the voltage frequency were analyzed. The results confirm that cell patterns are successfully created with the microchip and this microchip offers an easy method to fabricate cell patterns on a substrate for characterization.

Original languageEnglish
Title of host publication2018 IEEE International Conference on Robotics and Biomimetics, ROBIO 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1521-1526
Number of pages6
ISBN (Electronic)9781728103761
DOIs
Publication statusPublished - 2 Jul 2018
Event2018 IEEE International Conference on Robotics and Biomimetics, ROBIO 2018 - Kuala Lumpur, Malaysia
Duration: 12 Dec 201815 Dec 2018

Publication series

Name2018 IEEE International Conference on Robotics and Biomimetics, ROBIO 2018

Conference

Conference2018 IEEE International Conference on Robotics and Biomimetics, ROBIO 2018
Country/TerritoryMalaysia
CityKuala Lumpur
Period12/12/1815/12/18

ASJC Scopus subject areas

  • Biotechnology
  • Artificial Intelligence
  • Human-Computer Interaction

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