Cascaded Robust Learning at Imperfect Labels for Chest X-ray Segmentation

Cheng Xue, Qiao Deng, Xiaomeng Li, Qi Dou, Pheng Ann Heng

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

21 Citations (Scopus)


The superior performance of CNN on medical image analysis heavily depends on the annotation quality, such as the number of labeled images, the source of images, and the expert experience. The annotation requires great expertise and labor. To deal with the high inter-rater variability, the study of the imperfect label has great significance in medical image segmentation tasks. In this paper, we present a novel cascaded robust learning framework for chest X-ray segmentation with imperfect annotation at the boundary. Our model consists of three independent networks, which can effectively learn useful information from peer networks. The framework includes two stages. In the first stage, we select the clean annotated samples via a model committee setting, the networks are trained by minimizing a segmentation loss using the selected clean samples. In the second stage, we design a joint optimization framework with label correction to gradually correct the wrong annotation and improve the network performance. We conduct experiments on the public chest X-ray image datasets collected by Shenzhen Hospital. The results show that our methods could achieve a significant improvement on the accuracy in segmentation tasks compared to the previous methods.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2020 - 23rd International Conference, Proceedings
EditorsAnne L. Martel, Purang Abolmaesumi, Danail Stoyanov, Diana Mateus, Maria A. Zuluaga, S. Kevin Zhou, Daniel Racoceanu, Leo Joskowicz
PublisherSpringer Science and Business Media Deutschland GmbH
Number of pages10
ISBN (Print)9783030597245
Publication statusPublished - 2020
Externally publishedYes
Event23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020 - Lima, Peru
Duration: 4 Oct 20208 Oct 2020

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12266 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020


  • Imperfect label
  • Lung segmentation
  • Robust learning

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)


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