Bismuth and metal-doped bismuth nanoparticles produced by laser ablation for electrochemical glucose sensing

Weiran Zheng, Yong Li, Lawrence Yoon Suk Lee

Research output: Journal article publicationJournal articleAcademic researchpeer-review


Materials based on transition metals, such as Cu, Co, and Ni, have been intensively used as electrocatalysts for non-enzymatic electrochemical glucose sensing. However, the current trend of wearable/in vivo continuous glucose sensing has raised the need for non/low-toxic candidates. Herein, we demonstrate that the overlooked low-toxic bismuth (Bi)-based nanomaterials are suitable choices. Using a laser-ablation method, surfactant-free Bi nanoparticles (NPs) and transition metal (Ni and Co)-doped Bi NPs are obtained, achieving amperometric sensitivity values of 127, 677, and 2326 µA mM−1 cm−2, respectively. Low detection limits of 1 and 4 µM, as well as an extensive linear range of 0.001–3.5 mM, are recorded using Ni- and Co-doped Bi NPs, respectively. With competitive performance and high selectivity towards glucose sensing in both standard and serum samples, Bi-based nanomaterials are proven effective and promising candidates for future glucose sensor design beyond transition metal elements.

Original languageEnglish
Article number131334
JournalSensors and Actuators B: Chemical
Publication statusPublished - 15 Apr 2022


  • Amperometry
  • Bismuth nanoparticle
  • Glucose sensor
  • Laser ablation
  • Metal doping

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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