Objective: To acquire myocardium associated mechanical properties by directly quantifying stiffness of myocardium in vivo. An intervention stiffness detection system for biomechanics assessment of myocardium in vivo was established. Methods: The equipment was composed of intervention ultrasound stiffness detection catheter, physiological signal unit and mainframe. Under X-ray perspective, catheter passed through peripheral artery and entered into left-ventricle of dog, and then impressed left-ventricle wall. Tissue thickness deformation was determined from the ultrasound echo and the pressure value was also gained by pressure transducer. According to strain-stress relation, the term of myocardium tissue stiffness may be obtained. Results: By using the equipment, myocardium. stiffness of left-ventricle apex and free wall were (40.55 ± 4.75) kPa and (36.02±7.03) kPa respectively. Conclusion: The equipment offered a method for directly quantifying myocardium stiffness in vivo and clinical application for detecting local or whole myocardium diastolic and systolic insufficiency. Meanwhile it may be also used for detecting deep tissue stiffness.
- Radiology, interventional
- Stiffness detection systen
- Stress strain relation
- Radiology Nuclear Medicine and imaging
- Physiology (medical)