Biomechanical analysis of lumbar interbody fusion supplemented with various posterior stabilization systems

Wei Fan, Li Xin Guo, Ming Zhang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

20 Citations (Scopus)


Purpose: Biomechanical comparison between rigid and non-rigid posterior stabilization systems following lumbar interbody fusion has been conducted in several studies. However, most of these previous studies mainly focused on investigating biomechanics of adjacent spinal segments or spine stability. The objective of the present study was to compare biomechanical responses of the fusion devices when using different posterior instrumentations. Methods: Finite-element model of the intact human lumbar spine (L1–sacrum) was modified to simulate implantation of the fusion cage at L4–L5 level supplemented with different posterior stabilization systems including (i) pedicle screw-based fixation using rigid connecting rods (titanium rods), (ii) pedicle screw-based fixation using flexible connecting rods (PEEK rods) and (iii) dynamic interspinous spacer (DIAM). Stress responses were compared among these various models under bending moments. Results: The highest and lowest stresses in endplate, fusion cage and bone graft were found at the fused L4–L5 level with DIAM and titanium rod stabilization systems, respectively. When using PEEK rod for the pedicle screw fixation, peak stress in the pedicle screw was lower but the ratio of peak stress in the rods to yield stress of the rod material was higher than using titanium rod. Conclusions: Compared with conventional rigid posterior stabilization system, the use of non-rigid stabilization system (i.e., the PEEK rod system and DIAM system) following lumbar interbody fusion might increase the risks of cage subsidence and cage damage, but promote bony fusion due to higher stress in the bone graft. For the pedicle screw-based rod stabilization system, using PEEK rod might reduce the risk of screw breakage but increased breakage risk of the rod itself.

Original languageEnglish
Pages (from-to)2342-2350
Number of pages9
JournalEuropean Spine Journal
Issue number8
Publication statusPublished - 4 May 2021


  • Biomechanics
  • Finite element
  • Lumbar interbody fusion
  • Non-rigid stabilization system
  • Rigid stabilization system

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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