Biodegradation of tricresyl phosphates isomers by a novel microbial consortium and the toxicity evaluation of its major products

Yuanyuan Yu, Wentao Mo, Xifen Zhu, Xiaolong Yu, Jianteng Sun, Fucai Deng, Ling Jin, Hua Yin, Lizhong Zhu

Research output: Journal article publicationJournal articleAcademic researchpeer-review

Abstract

A novel microbial consortium ZY1 capable of degrading tricresyl phosphates (TCPs) was isolated, it could quickly degrade 100% of 1 mg/L tri-o-cresyl phosphate (ToCP), tri-p-cresyl phosphate (TpCP) and tri-m-cresyl phosphate (TmCP) within 36, 24 and 12 h separately and intracellular enzymes occupied the dominated role in TCPs biodegradation. Additionally, triphenyl phosphate (TPHP), 2-ethylhexyl diphenyl phosphate (EHDPP), bisphenol-A bis (diphenyl phosphate) (BDP), tris (2-chloroethyl) phosphate (TCEP) and tris (1-chloro-2-propyl) phosphate (TCPP) could also be degraded by ZY1 and the aryl-phosphates was easier to be degraded. The TCPs reduction observed in freshwater and seawater indicated that high salinity might weak the degradability of ZY1. The detected degradation products suggested that TCPs was mainly metabolized though the hydrolysis and hydroxylation. Sequencing analysis presented that the degradation of TCPs relied on the cooperation between sphingobacterium, variovorax and flavobacterium. The cytochrome P450/NADPH-cytochrome P450 reductase and phosphatase were speculated might involve in TCPs degradation. Finally, toxicity evaluation study found that the toxicity of the diesters products was lower than their parent compound based on the generation of the intracellular reactive oxygen (ROS) and the apoptosis rate of A549 cell. Taken together, this research provided a new insight for the bioremediation of TCPs in actual environment.
Original languageEnglish
Article number154415
JournalScience of the Total Environment
Volume828
DOIs
Publication statusPublished - 1 Jul 2022

Keywords

  • Bioaugmentation
  • Metabolic pathways
  • Microbial community
  • Toxicity
  • Tricresyl phosphates

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

Fingerprint

Dive into the research topics of 'Biodegradation of tricresyl phosphates isomers by a novel microbial consortium and the toxicity evaluation of its major products'. Together they form a unique fingerprint.

Cite this