Biocompatible antimicrobial cotton modified with tricarbimide-based N-halamine

Lin Li, Kaikai Ma, Ying Liu, Zhiwei Xie, T. S. Huang, Xuehong Ren (Corresponding Author)

Research output: Journal article publicationJournal articleAcademic researchpeer-review

14 Citations (Scopus)

Abstract

Two N-halamine precursors, 1-glycidyl-s-triazine-2,4,6-trione and 1-(2,3-dihydroxypropyl)-s-triazine-2,4,6-trione, were synthesized and tethered onto cotton fabrics via the crosslinking agent 1,2,3,4-butanetetracarboxylic acid. The modified samples were characterized by Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscope (SEM). The modified fabrics were rendered biocidal activities upon exposure to dilute hypochlorite solutions. The chlorinated cotton swatches were challenged with Staphylococcus aureus (ATCC 6538) and Escherichia coli O157:H7 (ATCC 43895) and exhibited excellent biocidal efficacy. The stability and rechargeability of the modified samples during washing and ultraviolet irradiation were also investigated. In vitro cell cytocompatibility studies demonstrated that the antibacterial cotton has good biocompatibility.

Original languageEnglish
Pages (from-to)963-968
Number of pages6
JournalPolymers for Advanced Technologies
Volume25
Issue number9
DOIs
Publication statusPublished - Sept 2014
Externally publishedYes

Keywords

  • Biocidal
  • Biomaterials
  • Cellulose
  • N-halamine
  • Tricarbimide

ASJC Scopus subject areas

  • Polymers and Plastics

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