Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites

Hongquan Zhang; Ming Zhang; Yuhui Shen; Haobo Pan; Kuibo Zhang; William W. Lu

doi:10.1109/BMEI.2010.5639603

Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites

Hongquan Zhang, Ming Zhang, Yuhui Shen, Haobo Pan, Kuibo Zhang, William W. Lu

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

3 Citations (Scopus)

Abstract

Novel bioactive bis-GMA-based resin composites were successfully developed by incorporating hydroxyapatite (HA) whiskers in the polymeric matrix. The whiskers had good dispersibility and wettability with bis-GMA-based polymer, showing good bonding with the matrix, which conferred good reinforcement. The mechanical properties of the composites were significantly enhanced when compared with the particulate filler. The morphology change of HA did not cause obvious variations in the proliferation and viability of L929 cells and the apatite-forming ability of the composites in SBF. The in vitro cytotoxicity of the composites was depressed by addition of hydroxyapatite filing materials. Such a favorable response indicated an important similarity in surface chemistry of the HA filler, and HA whiskers appeared to have potential as most promising reinforcements for resin-based polymers.

Original language	English
Title of host publication	Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010
Pages	1640-1644
Number of pages	5
Volume	4
DOIs	https://doi.org/10.1109/BMEI.2010.5639603
Publication status	Published - 1 Dec 2010
Event	3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010 - Yantai, China Duration: 16 Oct 2010 → 18 Oct 2010

Conference

Conference	3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010
Country/Territory	China
City	Yantai
Period	16/10/10 → 18/10/10

Keywords

Apatite-forming ability
Hydroxyapatite whiskers
In vitro biocompatibility
Resin composite

ASJC Scopus subject areas

Biomedical Engineering
Health Informatics
Health Information Management

More information

10.1109/BMEI.2010.5639603

Cite this

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title = "Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites",

abstract = "Novel bioactive bis-GMA-based resin composites were successfully developed by incorporating hydroxyapatite (HA) whiskers in the polymeric matrix. The whiskers had good dispersibility and wettability with bis-GMA-based polymer, showing good bonding with the matrix, which conferred good reinforcement. The mechanical properties of the composites were significantly enhanced when compared with the particulate filler. The morphology change of HA did not cause obvious variations in the proliferation and viability of L929 cells and the apatite-forming ability of the composites in SBF. The in vitro cytotoxicity of the composites was depressed by addition of hydroxyapatite filing materials. Such a favorable response indicated an important similarity in surface chemistry of the HA filler, and HA whiskers appeared to have potential as most promising reinforcements for resin-based polymers.",

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author = "Hongquan Zhang and Ming Zhang and Yuhui Shen and Haobo Pan and Kuibo Zhang and Lu, {William W.}",

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Zhang, H, Zhang, M, Shen, Y, Pan, H, Zhang, K & Lu, WW 2010, Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites. in Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. vol. 4, 5639603, pp. 1640-1644, 3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010, Yantai, China, 16/10/10. https://doi.org/10.1109/BMEI.2010.5639603

Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites. / Zhang, Hongquan; Zhang, Ming; Shen, Yuhui et al.
Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. Vol. 4 2010. p. 1640-1644 5639603.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

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AU - Zhang, Ming

AU - Shen, Yuhui

AU - Pan, Haobo

AU - Zhang, Kuibo

AU - Lu, William W.

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Biocompatibility and bioactivity of hydroxyapatite whiskers reinforced bis-GMA based composites

Abstract

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Keywords

ASJC Scopus subject areas

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