Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Kam L. Wong; Ricky N.S. Wong; Liang Zhang; Wing K. Liu; Tzi B. NG; Pang C. Shaw; Philip Chi L. Kwok; Yau Ming Lai; Zhang J. Zhang; Yanbo Zhang; Yao Tong; Ho Pan Cheung; Jia Lu; Stephen Cho W. Sze

doi:10.1186/1749-8546-9-19

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Kam L. Wong, Ricky N.S. Wong, Liang Zhang, Wing K. Liu, Tzi B. NG, Pang C. Shaw, Philip Chi L. Kwok, Yau Ming Lai, Zhang J. Zhang, Yanbo Zhang, Yao Tong, Ho Pan Cheung, Jia Lu, Stephen Cho W. Sze

Research output: Journal article publication › Review article › Academic research › peer-review

28 Citations (Scopus)

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

Original language	English
Article number	19
Journal	Chinese Medicine (United Kingdom)
Volume	9
Issue number	1
DOIs	https://doi.org/10.1186/1749-8546-9-19
Publication status	Published - 19 Jul 2014

ASJC Scopus subject areas

Pharmacology
Complementary and alternative medicine

More information

10.1186/1749-8546-9-19

Cite this

Wong, Kam L. ; Wong, Ricky N.S. ; Zhang, Liang ; Liu, Wing K. ; NG, Tzi B. ; Shaw, Pang C. ; Kwok, Philip Chi L. ; Lai, Yau Ming ; Zhang, Zhang J. ; Zhang, Yanbo ; Tong, Yao ; Cheung, Ho Pan ; Lu, Jia ; Sze, Stephen Cho W. / Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. In: Chinese Medicine (United Kingdom). 2014 ; Vol. 9, No. 1.

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title = "Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential",

abstract = "Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.",

author = "Wong, {Kam L.} and Wong, {Ricky N.S.} and Liang Zhang and Liu, {Wing K.} and NG, {Tzi B.} and Shaw, {Pang C.} and Kwok, {Philip Chi L.} and Lai, {Yau Ming} and Zhang, {Zhang J.} and Yanbo Zhang and Yao Tong and Cheung, {Ho Pan} and Jia Lu and Sze, {Stephen Cho W.}",

year = "2014",

month = jul,

day = "19",

doi = "10.1186/1749-8546-9-19",

language = "English",

volume = "9",

journal = "Chinese Medicine",

issn = "1749-8546",

publisher = "BioMed Central Ltd.",

number = "1",

}

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. / Wong, Kam L.; Wong, Ricky N.S.; Zhang, Liang; Liu, Wing K.; NG, Tzi B.; Shaw, Pang C.; Kwok, Philip Chi L.; Lai, Yau Ming; Zhang, Zhang J.; Zhang, Yanbo; Tong, Yao; Cheung, Ho Pan; Lu, Jia; Sze, Stephen Cho W.

In: Chinese Medicine (United Kingdom), Vol. 9, No. 1, 19, 19.07.2014.

Research output: Journal article publication › Review article › Academic research › peer-review

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AU - Wong, Ricky N.S.

AU - Zhang, Liang

AU - Liu, Wing K.

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AU - Shaw, Pang C.

AU - Kwok, Philip Chi L.

AU - Lai, Yau Ming

AU - Zhang, Zhang J.

AU - Zhang, Yanbo

AU - Tong, Yao

AU - Cheung, Ho Pan

AU - Lu, Jia

AU - Sze, Stephen Cho W.

PY - 2014/7/19

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AB - Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.

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