Abstract
A new switch-on fluorescent probe containing the natural product cryptolepine analogue benzofuroquinolinium moiety (binding scaffold) and a benzothiazole moiety (signalling unit) shows a remarkable fluorescence enhancement selective for the G-quadruplex nucleic acid structure. Binding studies revealed that the highly selective response of the fluorescent probe arises from end-stack binding to G-quadruplex.
| Original language | English |
|---|---|
| Pages (from-to) | 4971-4973 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Volume | 47 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - 7 May 2011 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
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