Abstract
An easily accessible chiral lr/H8-binapo catalyst exhibits unprecedented reactivity and excellent enantioselectivity in the hydrogenation of quinoxalines at a high ratio of substrate to catalyst (from 100 to 20000). This new method provides a practical synthetic approach to give optically active chiral tetrahydroquinoxaline derivatives (see scheme; cod = l, 5-cyclooctadiene).
Original language | English |
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Pages (from-to) | 9135-9138 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 48 |
DOIs | |
Publication status | Published - 16 Nov 2009 |
Keywords
- Asymmetric catalysis
- Diphosphinite ligands
- Hydrogenation
- Tetrahydroquinoxalines
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)