Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio

Wei Jun Tang; Shou Fei Zhu; Li Jin Xu; Qi Lin Zhou; Qing Hua Fan; Hai Feng Zhou; Kimhung Lam; Albert S.C. Chan

doi:10.1039/b614446b

Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio

Wei Jun Tang
, Shou Fei Zhu
, Li Jin Xu
, Qi Lin Zhou
, Qing Hua Fan
, Hai Feng Zhou
, Kimhung Lam
, Albert S.C. Chan

Research output: Journal article publication › Journal article › Academic research › peer-review

119 Citations (Scopus)

Abstract

The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane- 7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94% ee).

Original language	English
Pages (from-to)	613-615
Number of pages	3
Journal	Chemical Communications
Issue number	6
DOIs	https://doi.org/10.1039/b614446b
Publication status	Published - 12 Feb 2007

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b614446b

Cite this

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title = "Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio",

abstract = "The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane- 7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94\% ee).",

author = "Tang, \{Wei Jun\} and Zhu, \{Shou Fei\} and Xu, \{Li Jin\} and Zhou, \{Qi Lin\} and Fan, \{Qing Hua\} and Zhou, \{Hai Feng\} and Kimhung Lam and Chan, \{Albert S.C.\}",

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doi = "10.1039/b614446b",

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journal = "Chemical Communications",

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AU - Tang, Wei Jun

AU - Zhu, Shou Fei

AU - Xu, Li Jin

AU - Zhou, Qi Lin

AU - Fan, Qing Hua

AU - Zhou, Hai Feng

AU - Lam, Kimhung

AU - Chan, Albert S.C.

PY - 2007/2/12

Y1 - 2007/2/12

N2 - The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane- 7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94% ee).

AB - The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane- 7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94% ee).

UR - https://www.scopus.com/pages/publications/33846816454

U2 - 10.1039/b614446b

DO - 10.1039/b614446b

M3 - Journal article

AN - SCOPUS:33846816454

SN - 1359-7345

SP - 613

EP - 615

JO - Chemical Communications

JF - Chemical Communications

IS - 6

ER -

Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio

Abstract

ASJC Scopus subject areas

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