Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio

Wei Jun Tang, Shou Fei Zhu, Li Jin Xu, Qi Lin Zhou, Qing Hua Fan, Hai Feng Zhou, Kimhung Lam, Albert S.C. Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

103 Citations (Scopus)

Abstract

The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane- 7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94% ee).

Original languageEnglish
Pages (from-to)613-615
Number of pages3
JournalChemical Communications
Issue number6
DOIs
Publication statusPublished - 12 Feb 2007

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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