Asymmetric epoxidation of N-enoylsultams with urea-hydrogen peroxide/trifluoroacetic anhydride

Jia Zhang Shu, Hong Chan Wing, Albert W M Lee, Wai Yeung Wong, Viktor O. Rogatchov, Peter Metz

Research output: Journal article publicationJournal articleAcademic researchpeer-review


Diastereomeric isomers of epoxides 15-28 are obtained in high yield and moderate to high optical purity when N-enoylsultams 1-14 incorporating a variety of chiral sultams as the chiral induction elements are treated with urea-hydrogen peroxide/trifluoroacetic anhydride.
Original languageEnglish
Pages (from-to)755-756
Number of pages2
JournalJournal of Chemical Research
Issue number12
Publication statusPublished - 1 Dec 2005
Externally publishedYes


  • Asymmetric epoxidation
  • Auxiliary
  • Chiral sultam
  • Synthesis
  • Urea hydrogen peroxide

ASJC Scopus subject areas

  • Chemistry(all)

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