@inproceedings{8e76d67134904f3c9b3d92ddabbc3bf9,
title = "Application of thermosensitive poloxamer-based hydrogel in the development of transdermal therapy containing herbal medicine",
abstract = "Poloxamer 407 exhibits remarkable reversible sol gel transition which makes it attractive and promising in the application of transdermal therapy. This study mainly reports the skin permeation properties of model drug from poloxamer 407 based transdermal hydrogel therapy with the presence of chemical penetration enhancers. Poloxamer 407 based hydrogel was shown porous structure which faciliates the diffusional release of model drug. Compared with borneol and 1,2-propanediol, azone was the most effective enhancer for gallic acid skin permeation, and 3% of azone presented the optimal enhancement effect. This study also demonstrated that the selection of enhancers is of great importance for the skin permeation of model drug.",
keywords = "Azone, Chemical enhancer, Poloxamer hydrogel, Transdermal therapy",
author = "Wenyi Wang and Hui, {Patrick C.L.} and Ng, {Frency S.F.} and Kan, {Chi Wai} and Lau, {Clara B.S.} and Leung, {Ping Chung}",
note = "Publisher Copyright: {\textcopyright} 2017 Trans Tech Publications.; International Conference on Advanced Materials Research and Manufacturing Technologies, AMRMT 2016 ; Conference date: 18-08-2016 Through 20-08-2016",
year = "2017",
doi = "10.4028/www.scientific.net/KEM.719.57",
language = "English",
isbn = "9783035710052",
series = "Key Engineering Materials",
publisher = "Trans Tech Publications Ltd",
pages = "57--61",
editor = "Lau, {Alan Kin Tak} and Zengtao Chen",
booktitle = "Advanced Materials Research and Technologies",
}