TY - JOUR
T1 - Applicability of Equilibrium Sampling in Informing Tissue Residues and Dietary Risks of Legacy and Current-Use Organic Chemicals in Aquaculture
AU - Li, Juan ying
AU - Zhang, Li
AU - Wang, Qian
AU - Xu, Jiayan
AU - Yin, Jie
AU - Chen, Yiqin
AU - Gong, Yiwen
AU - Kelly, Barry C.
AU - Jin, Ling
N1 - Funding Information:
The present study is funded by the Shanghai Science and Technology Committee (18050502100), the Doctoral Research Foundation of Shanghai Ocean University (A2‐2006‐00‐200366), and the Special Fund for Science and Technology Development of Shanghai Ocean University (A2‐2006‐00‐200219). Special thanks go to Dr. Chen of ExxonMobil biomedical sciences for a critical review of the study.
Publisher Copyright:
© 2020 SETAC
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/1
Y1 - 2021/1
N2 - Equilibrium sampling based on silicone polydimethylsiloxane (PDMS) has been used to determine the concentrations of freely dissolved hydrophobic organic compounds (HOCs) and assess the thermodynamic potentials for bioaccumulation of these compounds in the aquatic environment. This allows the use of PDMS-based sampling techniques in assisting conventional sampling and extraction methods for the determination of the concentrations of HOCs in aquaculture products. The present study is an ex situ demonstration of how well PDMS can inform the tissue residues and dietary risks of legacy or current-use organic chemicals in aquaculture species from farm ponds in eastern China. For legacy contaminants such as polybrominated diphenyl ethers (PBDEs, n = 10), good agreement between the predicted concentrations based on PDMS and the measured lipid-normalized concentrations was observed for 60% of the studied biota, including both pelagic and benthic species. For pesticides currently used, such as pyrethroid (PE) (n = 4) and organophosphate pesticides (OPPs, n = 7), the measured tissue residues were consistently higher than those predicted by PDMS, possibly caused by the continuous input from the surroundings. For the organochlorine pesticides (OCPs, n = 5), the only detected chemical was also underestimated. Adjusted by ingestion rates of aquaculture products and toxicology data, the target hazard quotients of these chemicals predicted from PDMS were generally comparable to those derived from measured concentrations in tissue because of the predominance of PBDEs. Overall, PDMS-based equilibrium sampling offered an alternative approach for the prediction of tissue residues and dietary risks of PBDEs. Moreover, it should be applied with caution for PEs, OPPs, and OCPs. Improving the application of PDMS for these chemicals in farm ponds warrants future study. Environ Toxicol Chem 2021;40:79–87.
AB - Equilibrium sampling based on silicone polydimethylsiloxane (PDMS) has been used to determine the concentrations of freely dissolved hydrophobic organic compounds (HOCs) and assess the thermodynamic potentials for bioaccumulation of these compounds in the aquatic environment. This allows the use of PDMS-based sampling techniques in assisting conventional sampling and extraction methods for the determination of the concentrations of HOCs in aquaculture products. The present study is an ex situ demonstration of how well PDMS can inform the tissue residues and dietary risks of legacy or current-use organic chemicals in aquaculture species from farm ponds in eastern China. For legacy contaminants such as polybrominated diphenyl ethers (PBDEs, n = 10), good agreement between the predicted concentrations based on PDMS and the measured lipid-normalized concentrations was observed for 60% of the studied biota, including both pelagic and benthic species. For pesticides currently used, such as pyrethroid (PE) (n = 4) and organophosphate pesticides (OPPs, n = 7), the measured tissue residues were consistently higher than those predicted by PDMS, possibly caused by the continuous input from the surroundings. For the organochlorine pesticides (OCPs, n = 5), the only detected chemical was also underestimated. Adjusted by ingestion rates of aquaculture products and toxicology data, the target hazard quotients of these chemicals predicted from PDMS were generally comparable to those derived from measured concentrations in tissue because of the predominance of PBDEs. Overall, PDMS-based equilibrium sampling offered an alternative approach for the prediction of tissue residues and dietary risks of PBDEs. Moreover, it should be applied with caution for PEs, OPPs, and OCPs. Improving the application of PDMS for these chemicals in farm ponds warrants future study. Environ Toxicol Chem 2021;40:79–87.
KW - Aquaculture environment
KW - Bioavailability
KW - Polydimethylsiloxane
KW - Porewater
UR - http://www.scopus.com/inward/record.url?scp=85096695798&partnerID=8YFLogxK
U2 - 10.1002/etc.4912
DO - 10.1002/etc.4912
M3 - Journal article
C2 - 33090545
AN - SCOPUS:85096695798
SN - 0730-7268
VL - 40
SP - 79
EP - 87
JO - Environmental Toxicology and Chemistry
JF - Environmental Toxicology and Chemistry
IS - 1
ER -