Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

Alexander Filippi, Fobang Liu, Jake Wilson, Steven Lelieveld, Karsten Korschelt, Ting Wang, Yueshe Wang, Tobias Reich, Ulrich Pöschl, Wolfgang Tremel, Haijie Tong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

24 Citations (Scopus)


Cerium oxide nanoparticles (CeNPs) have been shown to exhibit antioxidant capabilities, but their efficiency in scavenging reactive oxygen species (ROS) and the underlying mechanisms are not yet well understood. In this study, cerium dioxide nanoparticles (CeNPs) and nanorods (CeNRs) were found to exhibit much stronger scavenging activity than ·OH generation in phosphate buffered saline (PBS) and surrogate lung fluid (SLF). The larger surface area and higher defect density of CeNRs may lead to higher ·OH scavenging activity than for CeNPs. These insights are important to understand the redox activity of cerium nanomaterials and provide clues to the role of CeNPs in biological and environmental processes.

Original languageEnglish
Pages (from-to)11077-11081
Number of pages5
JournalRSC Advances
Issue number20
Publication statusPublished - 2019
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this