Anti-confocal assessment of middle ear inflammation

David S. Jung, John A. Crowe, John P. Birchall, Michael Geoffrey Somekh, Chung W. See

Research output: Journal article publicationJournal articleAcademic researchpeer-review

3 Citations (Scopus)

Abstract

To improve the diagnostic prediction of recurrence of otitis media with e usion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed e ective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements.
Original languageEnglish
Article number#273691
Pages (from-to)230-242
Number of pages13
JournalBiomedical Optics Express
Volume8
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • Confocal microscopy
  • Imaging through turbid media
  • Medical and biological imaging
  • Otolaryngology

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

Cite this