Analytical comparison of different parts of Radix Angelicae Sinensis by gas chromatography coupled with mass spectrometry

Shui Yin Wei, Cheng Jian Xu, Kam Wah Mok, Hui Cao, Tsui Yan Lau, Foo Tim Chau

Research output: Journal article publicationJournal articleAcademic researchpeer-review

19 Citations (Scopus)

Abstract

The three parts of Radix Angelicae Sinensis (Danggui) were reported to have different therapeutic effects. In order to investigate their chemical compositions of different parts of Danggui, gas chromatography-mass spectrometry (GC-MS) combined with chemometrics data analysis was applied to provide a more detailed study. Subwindow factor analysis (SFA) and a modified augmented evolving window orthogonal projection (AEWOP) method were used to resolve the batch GC-MS data sets from the Danggui samples. Then, t-test, Wilcoxon rank sum test, and principal component analysis (PCA) were applied to carry out the comparison job. The results indicate which components are found to have significant differences among the three parts. These findings may be helpful for further research of the pharmacological activities of Danggui.
Original languageEnglish
Pages (from-to)232-238
Number of pages7
JournalJournal of Chromatography A
Volume1187
Issue number1-2
DOIs
Publication statusPublished - 11 Apr 2008

Keywords

  • Chemometrics
  • Danggui
  • Factor analysis
  • GC-MS
  • Radix Angelicae Sinensis

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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