Analysis of the topological characteristics of a protein-protein interaction network

Yuanyuan Sun, Yujie Zhao, Chi Kong Tse, Chung Ming Lau

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

1 Citation (Scopus)

Abstract

The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.
Original languageEnglish
Title of host publicationProceedings of the 5th International Workshop on Chaos-Fractals Theories and Applications, IWCFTA 2012
Pages127-130
Number of pages4
DOIs
Publication statusPublished - 1 Dec 2012
Event5th International Workshop on Chaos-Fractals Theories and Applications, IWCFTA 2012 - Dalian, Liaoning, China
Duration: 18 Oct 201221 Oct 2012

Conference

Conference5th International Workshop on Chaos-Fractals Theories and Applications, IWCFTA 2012
Country/TerritoryChina
CityDalian, Liaoning
Period18/10/1221/10/12

Keywords

  • correlations
  • fractal
  • PPI networks
  • scale-free
  • small-world
  • topological analysis

ASJC Scopus subject areas

  • Computational Theory and Mathematics
  • Applied Mathematics

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