TY - JOUR
T1 - An update on COVID-19 pandemic: the epidemiology, pathogenesis, prevention and treatment strategies
AU - Tsang, Hin Fung
AU - Chan, Lawrence Wing Chi
AU - Cho, William Chi Shing
AU - Yu, Allen Chi Shing
AU - Yim, Aldrin Kay Yuen
AU - Chan, Amanda Kit Ching
AU - Ng, Lawrence Po Wah
AU - Wong, Yin Kwan Evelyn
AU - Pei, Xiao Meng
AU - Li, Marco Jing Woei
AU - Wong, Sze Chuen Cesar
N1 - Funding Information:
This paper was not funded. We thank Dr. Liu Shao Haei for providing an updated information on the pathogenesis and prevention of the COVID-19.
Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021/7
Y1 - 2021/7
N2 - Introduction: To date, the transmission of Coronavirus Disease-2019 (COVID-19) is still uncontrollable with the fact that the numbers of confirmed and death cases are still increasing. Up to 1st October 2020, 33,842,281 confirmed cases and 1,010,634 confirmed deaths have been reported to the World Health Organization from 216 different countries, areas and territories. Despite the urgent demand for effective treatment strategies, there is still no specific antiviral treatment for COVID-19 and the treatment guidelines for COVID-19 vary between countries. Area covered: In this article, we summarized the current knowledge on COVID-19 and the pandemic worldwide. Moreover, the epidemiology, pathogenesis, prevention and different treatment options will be discussed so that we shall prepare ourselves better to fight with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Expert opinion: The situation of the COVID-19 pandemic is still unpredictable. There is no effective vaccine or specific anti-viral drug to treat serve COVID-19 patients. Combination therapies have shown promising clinical improvement. Repurposing FDA-approved drugs might be one of possible treatment options. Without specific treatment and vaccines for COVID-19, the most effective way to prevent from being infected is to generate an ecosystem with effective protection, precautions and preventive measures.
AB - Introduction: To date, the transmission of Coronavirus Disease-2019 (COVID-19) is still uncontrollable with the fact that the numbers of confirmed and death cases are still increasing. Up to 1st October 2020, 33,842,281 confirmed cases and 1,010,634 confirmed deaths have been reported to the World Health Organization from 216 different countries, areas and territories. Despite the urgent demand for effective treatment strategies, there is still no specific antiviral treatment for COVID-19 and the treatment guidelines for COVID-19 vary between countries. Area covered: In this article, we summarized the current knowledge on COVID-19 and the pandemic worldwide. Moreover, the epidemiology, pathogenesis, prevention and different treatment options will be discussed so that we shall prepare ourselves better to fight with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Expert opinion: The situation of the COVID-19 pandemic is still unpredictable. There is no effective vaccine or specific anti-viral drug to treat serve COVID-19 patients. Combination therapies have shown promising clinical improvement. Repurposing FDA-approved drugs might be one of possible treatment options. Without specific treatment and vaccines for COVID-19, the most effective way to prevent from being infected is to generate an ecosystem with effective protection, precautions and preventive measures.
KW - coronavirus Disease-2019
KW - COVID-19
KW - COVID-19 management
KW - COVID-19 treatment
KW - novel coronavirus
KW - SARS-CoV-2
KW - severe acute respiratory syndrome coronavirus 2
UR - http://www.scopus.com/inward/record.url?scp=85098589136&partnerID=8YFLogxK
U2 - 10.1080/14787210.2021.1863146
DO - 10.1080/14787210.2021.1863146
M3 - Review article
C2 - 33306423
AN - SCOPUS:85098589136
SN - 1478-7210
VL - 19
SP - 877
EP - 888
JO - Expert Review of Anti-Infective Therapy
JF - Expert Review of Anti-Infective Therapy
IS - 7
ER -
