An optofluidic diffusivity probe for real-time chemical reaction monitoring

H. T. Zhao, Y. Yang, L. K. Chin, W. M. Zhu, Z. H. Yang, H. X. Zhang, A. Q. Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

This paper reports a novel optofluidic approach to monitor chemical reactions in real-time. This approach is based on the fact that molecular size change in chemical reactions will lead to a change of the average diffusion coefficient. Here we use the diffusivity change as an indicator to monitor the progress of chemical reactions. The hydrolysis of maltose catalyzed by maltase is used as a demonstration. The results indicate that the optimum condition for maltase is at pH 6.0 and 35°C. This approach can be used to reduce the cost and simplify the procedure of reaction monitoring in chemical, pharmaceutical and process industries.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages2110-2112
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - Oct 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 26 Oct 201430 Oct 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Country/TerritoryUnited States
CitySan Antonio
Period26/10/1430/10/14

Keywords

  • Chemical reaction monitor
  • Diffusivity
  • Hydrolysis
  • Optofluidic

ASJC Scopus subject areas

  • Control and Systems Engineering

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