TY - GEN
T1 - An on-chip glass sphere resonator for label-free detection
AU - Yu, Y. F.
AU - Kanna, V.
AU - Bourouina, T.
AU - Ng, S. H.
AU - Yap, P. H.
AU - Liu, A. Q.
PY - 2010/1
Y1 - 2010/1
N2 - An on-chip glass sphere resonator with prism coupler in microchannel for label-free detection is presented in this paper. A micro glass sphere in polytetrafluoroethylene (PTFE) coated microchannel and two optical fibers for light input and output are integrated onto a polydimethylsiloxane (PDMS) chip. In the experiments, the glass spheres have diameters ranging from 50 μ m to 120 μ m and the PTFE films with thicknesses ranging from 200 nm to 1000 nm are coated for the tuning of coupling ratio. Experimental results show that the maximum quality factor (Q-factor) of the resonator reaches 3.1x103 and the measurements of refractive index has accuracy of 6x10-5 RIU, which corresponds to the label-free protein concentration detection with accuracy of 0.4 %. The on-chip glass sphere resonator has features as high stability, low cost, high sensitivity and label-free detection, which promises potential applications in environmental monitoring, real time chemical analysis and biological measurement.
AB - An on-chip glass sphere resonator with prism coupler in microchannel for label-free detection is presented in this paper. A micro glass sphere in polytetrafluoroethylene (PTFE) coated microchannel and two optical fibers for light input and output are integrated onto a polydimethylsiloxane (PDMS) chip. In the experiments, the glass spheres have diameters ranging from 50 μ m to 120 μ m and the PTFE films with thicknesses ranging from 200 nm to 1000 nm are coated for the tuning of coupling ratio. Experimental results show that the maximum quality factor (Q-factor) of the resonator reaches 3.1x103 and the measurements of refractive index has accuracy of 6x10-5 RIU, which corresponds to the label-free protein concentration detection with accuracy of 0.4 %. The on-chip glass sphere resonator has features as high stability, low cost, high sensitivity and label-free detection, which promises potential applications in environmental monitoring, real time chemical analysis and biological measurement.
UR - http://www.scopus.com/inward/record.url?scp=77952776660&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2010.5442277
DO - 10.1109/MEMSYS.2010.5442277
M3 - Conference article published in proceeding or book
AN - SCOPUS:77952776660
SN - 9781424457649
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 831
EP - 834
BT - MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest
T2 - 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
Y2 - 24 January 2010 through 28 January 2010
ER -