An OCT-based air suction-indentation probe for tissue elasticity measurement

Yongping Zheng, Like Wang, Tianjie Li, Yuanyuan Wang

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

2 Citations (Scopus)

Abstract

In this study, we developed a miniaturized optical coherence tomography (OCT) probe with a diameter of 4 mm. It was integrated with an air-jet indentation and air suction to induce deformation of tissue. The deforming process of tissue under suction or indentation was continuously monitored by OCT, and deformation of tissue was then derived from the transient OCT signals. Studies on phantoms with different stiffness were conducted. Results showed that the stiffness obtained by the OCT-based suction and indention well correlated with the stiffness detected using conventional mechanical testing. The probe was small enough for endoscopic use. In addition to the elasticity, the viscoelasticity of tissues can also be detected using creep indentation and suction test.
Original languageEnglish
Title of host publicationOptical Elastography and Tissue Biomechanics
PublisherSPIE
Volume8946
ISBN (Print)9780819498595
DOIs
Publication statusPublished - 1 Jan 2014
EventOptical Elastography and Tissue Biomechanics - San Francisco, CA, United States
Duration: 1 Feb 20142 Feb 2014

Conference

ConferenceOptical Elastography and Tissue Biomechanics
Country/TerritoryUnited States
CitySan Francisco, CA
Period1/02/142/02/14

Keywords

  • Air suction
  • Hysteresis
  • OCT
  • Tissue elasticity
  • Young's modulus

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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