An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues

Y. P. Huang; Yongping Zheng; S. Z. Wang

doi:10.1109/ISSMDBS.2008.4575058

An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues

Y. P. Huang, Yongping Zheng, S. Z. Wang

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

Abstract

A novel air jet indentation system with the combination of the optical coherence tomography (OCT) technique was presented in this paper for the quantitative measurement of mechanical properties of soft tissues. The key idea of this method is to use a pressure-measured air jet as an indenter to compress the soft tissue and utilize the OCT signals to extract the deformation induced. Experiments were performed on 27 silicon tissue-mimicking phantoms with different stiffness (Young's moduli, kPa) measured by uniaxial compression test. Regression coefficient of the indentation force to the indentation depth (N/mm) was used as an indicator of the stiffness under air jet indentation. Results showed that the stiffness coefficient measured by the current system well correlated with the Young's modulus of each phantom (r = 0.89, p<0.001). Preliminary in-vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in the tissue assessment and characterization where alterations of the mechanical properties are involved.

Original language	English
Title of host publication	Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008
Pages	220-223
Number of pages	4
DOIs	https://doi.org/10.1109/ISSMDBS.2008.4575058
Publication status	Published - 23 Sept 2008
Event	5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008 - Hong Kong, Hong Kong Duration: 1 Jun 2008 → 3 Jun 2008

Conference

Conference	5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008
Country/Territory	Hong Kong
City	Hong Kong
Period	1/06/08 → 3/06/08

ASJC Scopus subject areas

Biomedical Engineering
Electrical and Electronic Engineering

More information

10.1109/ISSMDBS.2008.4575058

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Huang, Y. P., Zheng, Y., & Wang, S. Z. (2008). An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues. In Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008 (pp. 220-223). Article 4575058 https://doi.org/10.1109/ISSMDBS.2008.4575058

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abstract = "A novel air jet indentation system with the combination of the optical coherence tomography (OCT) technique was presented in this paper for the quantitative measurement of mechanical properties of soft tissues. The key idea of this method is to use a pressure-measured air jet as an indenter to compress the soft tissue and utilize the OCT signals to extract the deformation induced. Experiments were performed on 27 silicon tissue-mimicking phantoms with different stiffness (Young's moduli, kPa) measured by uniaxial compression test. Regression coefficient of the indentation force to the indentation depth (N/mm) was used as an indicator of the stiffness under air jet indentation. Results showed that the stiffness coefficient measured by the current system well correlated with the Young's modulus of each phantom (r = 0.89, p<0.001). Preliminary in-vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in the tissue assessment and characterization where alterations of the mechanical properties are involved.",

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note = "5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008 ; Conference date: 01-06-2008 Through 03-06-2008",

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Huang, YP, Zheng, Y & Wang, SZ 2008, An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues. in Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008., 4575058, pp. 220-223, 5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008, Hong Kong, Hong Kong, 1/06/08. https://doi.org/10.1109/ISSMDBS.2008.4575058

An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues. / Huang, Y. P.; Zheng, Yongping; Wang, S. Z.
Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008. 2008. p. 220-223 4575058.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

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AU - Huang, Y. P.

AU - Zheng, Yongping

AU - Wang, S. Z.

PY - 2008/9/23

Y1 - 2008/9/23

N2 - A novel air jet indentation system with the combination of the optical coherence tomography (OCT) technique was presented in this paper for the quantitative measurement of mechanical properties of soft tissues. The key idea of this method is to use a pressure-measured air jet as an indenter to compress the soft tissue and utilize the OCT signals to extract the deformation induced. Experiments were performed on 27 silicon tissue-mimicking phantoms with different stiffness (Young's moduli, kPa) measured by uniaxial compression test. Regression coefficient of the indentation force to the indentation depth (N/mm) was used as an indicator of the stiffness under air jet indentation. Results showed that the stiffness coefficient measured by the current system well correlated with the Young's modulus of each phantom (r = 0.89, p<0.001). Preliminary in-vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in the tissue assessment and characterization where alterations of the mechanical properties are involved.

AB - A novel air jet indentation system with the combination of the optical coherence tomography (OCT) technique was presented in this paper for the quantitative measurement of mechanical properties of soft tissues. The key idea of this method is to use a pressure-measured air jet as an indenter to compress the soft tissue and utilize the OCT signals to extract the deformation induced. Experiments were performed on 27 silicon tissue-mimicking phantoms with different stiffness (Young's moduli, kPa) measured by uniaxial compression test. Regression coefficient of the indentation force to the indentation depth (N/mm) was used as an indicator of the stiffness under air jet indentation. Results showed that the stiffness coefficient measured by the current system well correlated with the Young's modulus of each phantom (r = 0.89, p<0.001). Preliminary in-vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in the tissue assessment and characterization where alterations of the mechanical properties are involved.

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M3 - Conference article published in proceeding or book

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BT - Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008

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Y2 - 1 June 2008 through 3 June 2008

ER -

Huang YP, Zheng Y, Wang SZ. An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues. In Proc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008. 2008. p. 220-223. 4575058 doi: 10.1109/ISSMDBS.2008.4575058

An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues

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