An OCT-based air jet indentation system for the measurement of mechanical properties of soft tissues

Y. P. Huang, Yongping Zheng, S. Z. Wang

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

A novel air jet indentation system with the combination of the optical coherence tomography (OCT) technique was presented in this paper for the quantitative measurement of mechanical properties of soft tissues. The key idea of this method is to use a pressure-measured air jet as an indenter to compress the soft tissue and utilize the OCT signals to extract the deformation induced. Experiments were performed on 27 silicon tissue-mimicking phantoms with different stiffness (Young's moduli, kPa) measured by uniaxial compression test. Regression coefficient of the indentation force to the indentation depth (N/mm) was used as an indicator of the stiffness under air jet indentation. Results showed that the stiffness coefficient measured by the current system well correlated with the Young's modulus of each phantom (r = 0.89, p<0.001). Preliminary in-vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in the tissue assessment and characterization where alterations of the mechanical properties are involved.
Original languageEnglish
Title of host publicationProc. 5th Int. Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th Int. Summer School and Symp. on Medical Devices and Biosensors, ISSS-MDBS 2008
Pages220-223
Number of pages4
DOIs
Publication statusPublished - 23 Sep 2008
Event5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008 - Hong Kong, Hong Kong
Duration: 1 Jun 20083 Jun 2008

Conference

Conference5th International Workshop on Wearable and Implantable Body Sensor Networks, BSN 2008, in conjunction with the 5th International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2008
CountryHong Kong
CityHong Kong
Period1/06/083/06/08

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering

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