An adjustable multi-scale single beam acoustic tweezers based on ultrahigh frequency ultrasonic transducer

Xiaoyang Chen, Kwok Ho Lam, Ruimin Chen, Zeyu Chen, Ping Yu, Zhongping Chen, K. Kirk Shung, Qifa Zhou

Research output: Journal article publicationJournal articleAcademic researchpeer-review

18 Citations (Scopus)


This paper reports the fabrication, characterization, and microparticle manipulation capability of an adjustable multi-scale single beam acoustic tweezers (SBAT) that is capable of flexibly changing the size of “tweezers” like ordinary metal tweezers with a single-element ultrahigh frequency (UHF) ultrasonic transducer. The measured resonant frequency of the developed transducer at 526 MHz is the highest frequency of piezoelectric single crystal based ultrasonic transducers ever reported. This focused UHF ultrasonic transducer exhibits a wide bandwidth (95.5% at −10 dB) due to high attenuation of high-frequency ultrasound wave, which allows the SBAT effectively excite with a wide range of excitation frequency from 150 to 400 MHz by using the “piezoelectric actuator” model. Through controlling the excitation frequency, the wavelength of ultrasound emitted from the SBAT can be changed to selectively manipulate a single microparticle of different sizes (3–100 μm) by using only one transducer. This concept of flexibly changing “tweezers” size is firstly introduced into the study of SBAT. At the same time, it was found that this incident ultrasound wavelength play an important role in lateral trapping and manipulation for microparticle of different sizes. Biotechnol. Bioeng. 2017;114: 2637–2647.
Original languageEnglish
Pages (from-to)2637-2647
Number of pages11
JournalBiotechnology and Bioengineering
Issue number11
Publication statusPublished - 1 Nov 2017


  • acoustic trapping
  • adjustable multi-scale tweezers
  • microparticle trapping and manipulation
  • ultrahigh frequency ultrasonic transducer
  • “piezoelectric actuator” model

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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