Amphiphilic polymeric particles with core-shell nanostructures: Emulsion-based syntheses and potential applications

Kin Man Ho, Wei Ying Li, Chun Him Wong, Pei Li

Research output: Journal article publicationReview articleAcademic researchpeer-review

94 Citations (Scopus)


The design and synthesis of amphiphilic nano- to micro-sized polymeric particles with core-shell nanostructures have attracted more and more attention because of their wide applicability in modern material science and their technological importance in the areas of colloid and interface science. Many synthetic strategies have been developed for the preparation of amphiphilic core-shell particles that consist of hydrophobic polymer cores and hydrophilic polymeric shells. In this review, we focus on emulsion-based approaches and properties of particles produced. These methods are: (1) grafting to functionalized particle that produces a corona-like particle, (2) grafting from reactive seed particle that produces a brush-like particle, (3) copolymerization of reactive macro-monomer with hydrophobic monomer that produces a corona-like particle, (4) emulsion polymerization in the presence of block or comb-like copolymer containing controlled free-radical moiety that produces a multi-layered particle, and (5) redox-initiated graft polymerization of vinyl monomer from a water-soluble polymer containing amino groups that produces a hairy-like particle. Potential applications of some of these particles in drug and gene deliveries, enzyme immobilization, colloidal nanocatalyst, chemical sensing, smart coating, and thermal laser imaging will be discussed.
Original languageEnglish
Pages (from-to)1503-1523
Number of pages21
JournalColloid and Polymer Science
Issue number16-17
Publication statusPublished - 1 Nov 2010


  • Amphiphilic core-shell particle
  • Application
  • Carrier
  • Catalysis
  • Coating
  • Sensing
  • Synthesis

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Colloid and Surface Chemistry
  • Materials Chemistry


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