Alzheimer’s disease: Insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China

Anita Yee, Nancy B.Y. Tsui, Y. N. Chang, Clarea S.M. Au, Manson Fok, L. T. Lau, Teresa Chung, Gregory Cheng, Rick Y.C. Kwan, Angela Y.M. Leung, Johnson Y.N. Lau, David L.K. Dai

Research output: Journal article publicationReview articleAcademic researchpeer-review

11 Citations (Scopus)


With the ageing of the global population, China is projected to be impacted significantly by the rising number of patients with Alzheimer’s disease (AD). A cure for AD is not yet available, so society should be prepared for an increasing AD-related burden. In this review, we examine this impending problem and provide overviews on (a) the magnitude of the problem of AD in Hong Kong/China in the near future; (b) the genetic and lifestyle risk factors that contribute to AD; (c) current diagnostic approaches and the potential of newly discovered genetic biomarkers for early detection; (d) medications, non-pharmacological interventions, and possible preventive measures; and (e) the need for social and psychological care from the community. In Hong Kong, primary care and AD-related support for at-risk individuals, patients, and caregivers are inadequate. A joint effort from the medical community, government, universities, non-governmental organisations/charities, and industry should initiate the development of a long-term programme for AD. Finally, we outline recommendations for the relevant. parties to consider.

Original languageEnglish
Pages (from-to)492-500
Number of pages9
JournalHong Kong Medical Journal
Issue number5
Publication statusPublished - Oct 2018

ASJC Scopus subject areas

  • Medicine(all)

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