Algorithmic scatter correction in dual-energy digital mammography for calcification imaging

Xi Chen, Robert M. Nishikawa, Suk Tak Chan, Beverly A. Lau, Lei Zhang, Xuanqin Mou

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

3 Citations (Scopus)


X-ray scatter leads to erroneous calculations of dual-energy digital mammography (DEDM). The purpose of this work is to design an algorithmic method for scatter correction in DEDM without extra exposures or lead sheet. The method was developed based on the knowledge that scatter radiation in mammograms varies slowly spatially and most pixels in mammograms are non-calcification pixels, and implemented on a commercial full-field digital mammography system with a phantom of breast tissue equivalent material. The pinhole-array interpolation scatter correction method was also implemented on the system. We compared the background dual-energy (DE) calcification signals in the DE calcification images. Results show that the background signal in the DE calcification image can be reduced. The rms of background DE calcification image signal of 1105μm with scatter-uncorrected data was reduced to 187μm and 253μm after scatter correction, using our algorithmic method and pinhole-array interpolation method, respectively. The range of background DE calcification signals using scatter-uncorrected data was reduced by ∼80% with scatter-corrected data using algorithmic method. The proposed algorithmic scatter correction method is effective; it has similar or even better performance than pinhole-array interpolation method in scatter correction for DEDM.

Original languageEnglish
Title of host publicationMedical Imaging 2012
Subtitle of host publicationPhysics of Medical Imaging
Publication statusPublished - 4 May 2012
EventMedical Imaging 2012: Physics of Medical Imaging - San Diego, CA, United States
Duration: 5 Feb 20128 Feb 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2012: Physics of Medical Imaging
Country/TerritoryUnited States
CitySan Diego, CA


  • calcification
  • digital mammography
  • dual-energy
  • scatter correction

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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