Various transmission control protocol (TCP) enhancement schemes have been proposed to improve TCP performance over mixed wired/wireless networks. Among the different kinds of TCP enhancement schemes, end-to-end TCP enhancement schemes have the lowest implementation complexity and do not violate the semantics of TCP. Their general principle is to distinguish wireless loss from congestion loss, and to take the cause of the loss into consideration when performing TCP congestion control. However, they do not consider the wireless loss probability which significantly affects their performance, mainly in terms of their throughputs. Before we proposed Dynamic Parameter Setting (DPS) to improve the performance of TCP by considering the effect of the wireless loss probability in parameter setting. In this paper, we propose a more aggressive approach to further improve the performance of TCP significantly by adjusting the policy to handle wireless loss. Our simulation experiments showed that ROTT, a popular end-to-end TCP enhancement scheme, with the new approach always outperformed the original ROTT in terms of throughput, and their differences could be more than three times better without having the fairness problem.