Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: Cellular characterisation and lysosome-specific localisation

Jiatao Wu; Yaqiong Li; Chunyan Tan; Xin Wang; Youming Zhang; Jun Song; Junle Qu; Wai Yeung Wong

doi:10.1039/c8cc06839a

Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: Cellular characterisation and lysosome-specific localisation

Jiatao Wu, Yaqiong Li, Chunyan Tan, Xin Wang, Youming Zhang, Jun Song, Junle Qu, Wai Yeung Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

44 Citations (Scopus)

Abstract

A novel near-infrared luminogen (TPE/TPY-Pt-PA/PEG) based on the terpyridyl Pt(ii) complex with a tetraphenylethene periphery is synthesised and characterised. It displays aggregation-induced emission with the formation of self-assembled nanostructures. The nanoparticles fabricated with TPE/TPY-Pt-PA/PEG show excellent biocompatibility with high specificity to lysosomes in HeLa cells.

Original language	English
Pages (from-to)	11144-11147
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	79
DOIs	https://doi.org/10.1039/c8cc06839a
Publication status	Published - 1 Jan 2018

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c8cc06839a

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AU - Li, Yaqiong

AU - Tan, Chunyan

AU - Wang, Xin

AU - Zhang, Youming

AU - Song, Jun

AU - Qu, Junle

AU - Wong, Wai Yeung

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AB - A novel near-infrared luminogen (TPE/TPY-Pt-PA/PEG) based on the terpyridyl Pt(ii) complex with a tetraphenylethene periphery is synthesised and characterised. It displays aggregation-induced emission with the formation of self-assembled nanostructures. The nanoparticles fabricated with TPE/TPY-Pt-PA/PEG show excellent biocompatibility with high specificity to lysosomes in HeLa cells.

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Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: Cellular characterisation and lysosome-specific localisation

Abstract

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