TY - JOUR
T1 - Acupuncture for de Quervain's tenosynovitis
T2 - A randomized controlled trial
AU - Leung, Kinking
AU - Ma, Oliver Chunho
AU - Qin, Zongshi
AU - Ting, Ho
AU - Lau, Andrew Hokay
AU - Lun, Kevin Kaifung
AU - Chan, Hanna Yufaye
AU - Wen, Grace Yagun
AU - Ng, Jetson Tszkit
AU - Chow, Lingfung
AU - Chu, Cody Yuenting
AU - Ho, Tracy Siuting
AU - Tsang, Katherine
AU - Ng, Bacon Fung Leung
AU - Fok, Margaret Woon Man
AU - Fang, Christian Xin Shuo
AU - Lao, Lixing
AU - Chen, Haiyong
N1 - Publisher Copyright:
© 2022 Elsevier GmbH
PY - 2022/9
Y1 - 2022/9
N2 - Background: Acupuncture has been an alternative approach for de Quervain's tenosynovitis (DQt), but trial evidence is still lacking. Purpose: This study aimed to assess the efficacy of acupuncture in patients with DQt. Study Design: A randomized controlled trial. Methods: A total of 68 subjects with DQt were recruited from outpatients of Department of Orthopaedics and Traumatology, and Chinese medicine clinics, The University of Hong Kong, and were randomized into the acupuncture group (n = 34) and the waitlist group (n = 34). Subjects in the acupuncture group received 5 acupuncture sessions over 2 weeks, followed by a 10-week follow-up. The waitlist control group received assessments only in the first 6 weeks of the waiting period and received the same acupuncture treatment and follow-up as the treatment group in the next 12 weeks. The primary outcome was the general pain intensity using the Visual Analogue Scale (VAS) at the end of treatment (week 2). Secondary outcomes were grip and pinch strengths of affected hands, the quick Disabilities of the Arm, Shoulder and Hand Score (Q-DASH), and the World Health Organization Quality of Life-brief Questionnaire (WHOQOL-BREF) at weeks 2 and 6. Results: From baseline to 2 weeks, the mean VAS score decreased by 19.5 points in the acupuncture group and by 3.4 points in the waitlist group. The difference for acupuncture vs waitlist control was -16.2 points (95% CI, -26.7 to -5.6, p = 0.003). Acupuncture effects sustained for 10 weeks (mean difference compared with baseline, -30.6; 95% CI, -39.6 to -21.7). Secondary outcomes showed that acupuncture reduced pain intensity, improved grip and pinch strength of affected hands, and Q-DASH scores, but not the scores of WHOQOL-BREF in patients. No serious adverse event occurred during the study period. Conclusions: Our findings support that 2-week of acupuncture is safe and effective in the reduction of pain intensity, and improvement of strengths and disabilities of hand in DQt patients. Acupuncture also has long-term effects on DQt. Trial registration: This study was registered at clinicaltrials.gov (NCT03472443).
AB - Background: Acupuncture has been an alternative approach for de Quervain's tenosynovitis (DQt), but trial evidence is still lacking. Purpose: This study aimed to assess the efficacy of acupuncture in patients with DQt. Study Design: A randomized controlled trial. Methods: A total of 68 subjects with DQt were recruited from outpatients of Department of Orthopaedics and Traumatology, and Chinese medicine clinics, The University of Hong Kong, and were randomized into the acupuncture group (n = 34) and the waitlist group (n = 34). Subjects in the acupuncture group received 5 acupuncture sessions over 2 weeks, followed by a 10-week follow-up. The waitlist control group received assessments only in the first 6 weeks of the waiting period and received the same acupuncture treatment and follow-up as the treatment group in the next 12 weeks. The primary outcome was the general pain intensity using the Visual Analogue Scale (VAS) at the end of treatment (week 2). Secondary outcomes were grip and pinch strengths of affected hands, the quick Disabilities of the Arm, Shoulder and Hand Score (Q-DASH), and the World Health Organization Quality of Life-brief Questionnaire (WHOQOL-BREF) at weeks 2 and 6. Results: From baseline to 2 weeks, the mean VAS score decreased by 19.5 points in the acupuncture group and by 3.4 points in the waitlist group. The difference for acupuncture vs waitlist control was -16.2 points (95% CI, -26.7 to -5.6, p = 0.003). Acupuncture effects sustained for 10 weeks (mean difference compared with baseline, -30.6; 95% CI, -39.6 to -21.7). Secondary outcomes showed that acupuncture reduced pain intensity, improved grip and pinch strength of affected hands, and Q-DASH scores, but not the scores of WHOQOL-BREF in patients. No serious adverse event occurred during the study period. Conclusions: Our findings support that 2-week of acupuncture is safe and effective in the reduction of pain intensity, and improvement of strengths and disabilities of hand in DQt patients. Acupuncture also has long-term effects on DQt. Trial registration: This study was registered at clinicaltrials.gov (NCT03472443).
KW - Acupuncture
KW - de Quervain's tenosynovitis
KW - Randomized controlled trial
KW - waitlist
UR - http://www.scopus.com/inward/record.url?scp=85133176261&partnerID=8YFLogxK
U2 - 10.1016/j.phymed.2022.154254
DO - 10.1016/j.phymed.2022.154254
M3 - Journal article
C2 - 35728386
AN - SCOPUS:85133176261
SN - 0944-7113
VL - 104
JO - Phytomedicine
JF - Phytomedicine
M1 - 154254
ER -