Accumulation of biodegradable copolyesters of 3-hydroxy-butyrate and 3- hydroxyvalerate in Alcaligenes eutrophus

H. Chua, P. H.F. Yu, Wai Hung Lo

Research output: Journal article publicationJournal articleAcademic researchpeer-review

12 Citations (Scopus)


Biodegradable copolyesters of 3-hydroxybutyrate-co-3-hydroxyvalerate (3HB-3HV) were produced by Alcaligenes eutrophus in a two-staged process, namely growth stage and nitrogen-deficient polyester-accumulation stage. When C5was used as the sole carbon source, the copolyester contained 43 mol % of 3HV. A range of copolyesters with 0-43 mol % of 3HV could be produced by using a medium containing different concentration ratios of butyric acid C4and C5. T(m) of PHB homopolymer was 177.6°C and that of copolyester with highest 3HV mol fraction of 43% was 99.0°C. C5concentration in the medium could be an effective means to control the polymeric composition and mechanical properties of the copolyesters accumulated in A. eutrophus.
Original languageEnglish
Pages (from-to)929-935
Number of pages7
JournalApplied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology
Publication statusPublished - 1 Jan 1998


  • Alcaligenes eutrophus H16
  • Biodegradable plastics
  • Physical properties
  • Poly (3-hydroxybutyrate-co-3-hydroxyvalerate)

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology

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