@inproceedings{efa1c31aca4b441cb535d6358ed060be,
title = "A study of axonal protein trafficking in neuronal networks via the microfluidic platform",
abstract = "This paper reports a microfluidic platform for culturing neuronal networks and the study of axonal protein trafficking. The device consists of cultural microchambers connected by microchannel array. Molecular biological methods were used to express fluorescent proteins in neurons. Preliminary results show that the neurons can be polarized with their soma and axons being compartmentalized into different fluidically isolated microenvironments. When chemical stimulation was applied to axonal chamber, anterograde migration of expressed fluorescent proteins could be observed. The platform will be useful in neuroscience research for studying the response of individual neurons to extracellular stimulation.",
keywords = "Axonal protein, Microfluidic, Neuron, Protein trafficking",
author = "Y. Fu and A. Vandongen and T. Bourouina and Tsang, \{W. M.\} and M. Je and Liu, \{A. Q.\}",
year = "2012",
month = nov,
language = "English",
isbn = "9780979806452",
series = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
publisher = "Chemical and Biological Microsystems Society",
pages = "1072--1074",
booktitle = "Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012",
note = "16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 ; Conference date: 28-10-2012 Through 01-11-2012",
}