A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging

Zhen Ling Wang; Jianhua Hao; Helen L.W. Chan; Wing Tak Wong; Ka Leung Wong

doi:10.1002/smll.201102703

A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging

Zhen Ling Wang
, Jianhua Hao
, Helen L.W. Chan
, Wing Tak Wong
, Ka Leung Wong

Research output: Journal article publication › Journal article › Academic research › peer-review

88 Citations (Scopus)

Abstract

Hexagonal-phase NaYF₄:Yb³⁺,Er³⁺ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

Original language	English
Pages (from-to)	1863-1868
Number of pages	6
Journal	Small
Volume	8
Issue number	12
DOIs	https://doi.org/10.1002/smll.201102703
Publication status	Published - 25 Jun 2012

Keywords

biosensors
fluorescent probes
imaging
lanthanide nanocrystals
phase transitions

ASJC Scopus subject areas

Biotechnology
Biomaterials
General Chemistry
General Materials Science

More information

10.1002/smll.201102703

Cite this

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title = "A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging",

abstract = "Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.",

keywords = "biosensors, fluorescent probes, imaging, lanthanide nanocrystals, phase transitions",

author = "Wang, \{Zhen Ling\} and Jianhua Hao and Chan, \{Helen L.W.\} and Wong, \{Wing Tak\} and Wong, \{Ka Leung\}",

year = "2012",

month = jun,

day = "25",

doi = "10.1002/smll.201102703",

language = "English",

volume = "8",

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journal = "Small",

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A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging. / Wang, Zhen Ling; Hao, Jianhua; Chan, Helen L.W. et al.
In: Small, Vol. 8, No. 12, 25.06.2012, p. 1863-1868.

Research output: Journal article publication › Journal article › Academic research › peer-review

TY - JOUR

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AU - Wang, Zhen Ling

AU - Hao, Jianhua

AU - Chan, Helen L.W.

AU - Wong, Wing Tak

AU - Wong, Ka Leung

PY - 2012/6/25

Y1 - 2012/6/25

N2 - Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

AB - Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation.

KW - biosensors

KW - fluorescent probes

KW - imaging

KW - lanthanide nanocrystals

KW - phase transitions

UR - https://www.scopus.com/pages/publications/84862572946

U2 - 10.1002/smll.201102703

DO - 10.1002/smll.201102703

M3 - Journal article

C2 - 22467196

SN - 1613-6810

VL - 8

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JF - Small

IS - 12

ER -

A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb 3+,Er3+ nanocrystals for in vitro cell imaging

Abstract

Keywords

ASJC Scopus subject areas

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