Abstract
A simple Schiff base fluorescent sensor (BDNOL) was synthesized from the reaction of picolinohydrazide and 4-(diethylamino)salicylaldehyde, and developed for selective detection of Al 3+ and Zn 2+ . This non-fluorescent sensor displayed obvious fluorescence enhancement after binding to Al 3+ /Zn 2+ ions with high sensitivity and selectivity, accompanied by obvious fluorescence emission enhancement (504 nm for Al 3+ and 575 nm for Zn 2+ ). The detection limits were found to be 8.30 × 10 -8 M for Al 3+ and 1.24 × 10 -7 M for Zn 2+ . The binding mechanisms between BDNOL and Al 3+ /Zn 2+ ions were supported by 1 H NMR and HR-MS analysis, and a density functional theory (DFT) study. The sensing behavior was also studied with molecular logic functions of OR, AND, and NOT gates. Furthermore, the fluorescent sensor was successfully used to recognize Al 3+ and Zn 2+ in living cells, suggesting that this simple biosensor has great potential in biological imaging applications.
Original language | English |
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Pages (from-to) | 5435-5442 |
Number of pages | 8 |
Journal | Journal of Materials Chemistry B |
Volume | 6 |
Issue number | 34 |
DOIs | |
Publication status | Published - 1 Jan 2018 |
ASJC Scopus subject areas
- General Chemistry
- Biomedical Engineering
- General Materials Science