A randomized controlled trial of self-regulated modified constraint-induced movement therapy in sub-acute stroke patients

K. P.Y. Liu (Corresponding Author), K. Balderi, T. L.F. Leung, A. S.Y. Yue, N. C.W. Lam, J. T.Y. Cheung, S. S.M. Fong, C. M.W. Sum, M. Bissett, R. Rye, V. C.T. Mok

Research output: Journal article publicationJournal articleAcademic researchpeer-review

19 Citations (Scopus)

Abstract

Background and purpose: Emerging research suggests the use of self-regulation (SR) for improving functional regain in patients post stroke. SR is proposed to produce an added effect to effective modified constraint-induced movement therapy (mCIMT). This study aimed to examine the effect of a self-regulated mCIMT programme (SR-mCIMT) for functional regain in patients with sub-acute stroke. Methods: Eighty-six patients completed the trial: SR-mCIMT, n = 29; mCIMT, n = 31; or conventional functional rehabilitation, n = 26. All interventions were 2-week therapist-guided training. Outcome measurements, taken by a blinded assessor, examined arm function [Action Research Arm Test (ARAT), Fugl-Meyer Assessment (FMA)], daily task performance [Lawton Instrumental Activities of Daily Living Scale (Lawton IADL)] and self-perceived arm use in functional tasks [Motor Activity Log (MAL)]. Results: Significant differences were found with the SR-mCIMT outperforming the other groups after the intervention (ARAT, P = 0.006; FMA, Lawton IADL and MAL, all Ps < 0.001). In terms of the carry-over effect, the SR-mCIMT group outperformed in the hand and coordination subscales of ARAT and FMA (P = 0.012–0.013) and the self-perceived quality of arm use (P = 0.002). Conclusion: A combination of SR and mCIMT could produce an added effect in functional regain in patients post stroke.

Original languageEnglish
Pages (from-to)1351-1360
Number of pages10
JournalEuropean Journal of Neurology
Volume23
Issue number8
DOIs
Publication statusPublished - Aug 2016
Externally publishedYes

Keywords

  • functional recovery
  • modified constraint-induced movement therapy
  • randomized controlled trial
  • self-regulation
  • stroke

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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