TY - JOUR
T1 - A prospective study of psychological distress after prostate cancer surgery
AU - Occhipinti, Stefano
AU - Zajdlewicz, Leah
AU - Coughlin, Geoffrey D.
AU - Yaxley, John W.
AU - Dunglison, Nigel
AU - Gardiner, Robert A.
AU - Chambers, Suzanne K.
N1 - Funding Information:
We thank Cancer Council Queensland for providing the grant for this research project, the patients for supporting this study, and the medical administration at Royal Brisbane & Women's Hospital.
Publisher Copyright:
© 2019 John Wiley & Sons, Ltd.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Background: Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care. Objective: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer. Design, Setting, and Participants: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post–surgery. Measurements: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data. Results and Limitations: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men. Conclusions: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.
AB - Background: Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care. Objective: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer. Design, Setting, and Participants: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post–surgery. Measurements: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data. Results and Limitations: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men. Conclusions: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.
KW - distress, longitudinal
KW - oncology, prostatectomy
KW - prostate cancer
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=85075174698&partnerID=8YFLogxK
U2 - 10.1002/pon.5263
DO - 10.1002/pon.5263
M3 - Journal article
C2 - 31659807
AN - SCOPUS:85075174698
SN - 1057-9249
VL - 28
SP - 2389
EP - 2395
JO - Psycho-Oncology
JF - Psycho-Oncology
IS - 12
ER -