A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

Jing Xiang Zhang; Hongguang Li; Chi Fai Chan; Rongfeng Lan; Wai Lun Chan; Ga Lai Law; Wai Kwok Wong; Ka Leung Wong

doi:10.1039/c2cc34963a

A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

Jing Xiang Zhang
, Hongguang Li
, Chi Fai Chan
, Rongfeng Lan
, Wai Lun Chan
, Ga Lai Law
, Wai Kwok Wong
, Ka Leung Wong

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

53 Citations (Scopus)

Abstract

An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (Φ_Δ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.

Original language	English
Pages (from-to)	9646-9648
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	77
DOIs	https://doi.org/10.1039/c2cc34963a
Publication status	Published - 29 Aug 2012

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc34963a

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abstract = "An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (ΦΔ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.",

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AU - Zhang, Jing Xiang

AU - Li, Hongguang

AU - Chan, Chi Fai

AU - Lan, Rongfeng

AU - Chan, Wai Lun

AU - Law, Ga Lai

AU - Wong, Wai Kwok

AU - Wong, Ka Leung

PY - 2012/8/29

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AB - An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (ΦΔ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.

UR - https://www.scopus.com/pages/publications/84865700019

U2 - 10.1039/c2cc34963a

DO - 10.1039/c2cc34963a

M3 - Journal article

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SN - 1359-7345

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JO - Chemical Communications

JF - Chemical Communications

IS - 77

ER -

A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

Abstract

ASJC Scopus subject areas

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