A potential water-soluble ytterbium-based porphyrin-cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

Jing Xiang Zhang, Hongguang Li, Chi Fai Chan, Rongfeng Lan, Wai Lun Chan, Ga Lai Law, Wai Kwok Wong, Ka Leung Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

36 Citations (Scopus)

Abstract

An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (ΦΔ= 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.
Original languageEnglish
Pages (from-to)9646-9648
Number of pages3
JournalChemical Communications
Volume48
Issue number77
DOIs
Publication statusPublished - 7 Oct 2012

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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