A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe3+with a wide linear concentration and its application in logic gate

Liang He, Jianna Li, John Haozhong Xin

Research output: Journal article publicationJournal articleAcademic researchpeer-review

45 Citations (Scopus)


A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe3+from Fe2+and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe3+concentration in a wide range of 0-120μM (correlation coefficient R2=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe3+and Fe2+. The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.
Original languageEnglish
Pages (from-to)69-73
Number of pages5
JournalBiosensors and Bioelectronics
Publication statusPublished - 5 Aug 2015


  • Cell imaging
  • Electron buffer
  • Graphene oxide
  • Logic gate
  • Nanosensor

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

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