A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe3+with a wide linear concentration and its application in logic gate

Liang He; Jianna Li; John Haozhong Xin

doi:10.1016/j.bios.2015.01.075

A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe³⁺with a wide linear concentration and its application in logic gate

Liang He, Jianna Li, John Haozhong Xin

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

49 Citations (Scopus)

Abstract

A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe3+from Fe2+and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe3+concentration in a wide range of 0-120μM (correlation coefficient R2=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe3+and Fe2+. The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.

Original language	English
Pages (from-to)	69-73
Number of pages	5
Journal	Biosensors and Bioelectronics
Volume	70
DOIs	https://doi.org/10.1016/j.bios.2015.01.075
Publication status	Published - 5 Aug 2015

Keywords

Cell imaging
Electron buffer
Graphene oxide
Logic gate
Nanosensor

ASJC Scopus subject areas

Biotechnology
Biophysics
Biomedical Engineering
Electrochemistry

More information

10.1016/j.bios.2015.01.075

Cite this

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title = "A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe3+with a wide linear concentration and its application in logic gate",

abstract = "A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe3+from Fe2+and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe3+concentration in a wide range of 0-120μM (correlation coefficient R2=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe3+and Fe2+. The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.",

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