A new method for computing the uniaxial modulus of articular cartilages using modified inhomogeneous triphasic model

Haijun Niu, Qing Wang, Yongping Zheng, Yubo Fan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

9 Citations (Scopus)


It is well known that subtle changes in structure and tissue composition of articular cartilage can lead to its degeneration. The present paper puts forward a modified layered inhomogeneous triphasic model with four parameters based on the inhomogeneous triphasic model proposed by Narmoneva et al. Incorporating a piecewise fitting optimization criterion, the new model was used to obtain the uniaxial modulus Ha, and predict swelling pattern for the articular cartilage based on ultrasound-measured swelling strain data. The results show that the new method can be used to provide more accurate estimation on the uniaxial modulus than the inhomogeneous triphasic model with three parameters and the homogeneous mode, and predict effectively the swelling strains of highly nonuniform distribution of degenerated articular cartilages. This study can provide supplementary information for exploring mechanical and material properties of the cartilage, and thus be helpful for the diagnosis of osteoarthritis-related diseases.
Original languageEnglish
Pages (from-to)121-126
Number of pages6
JournalActa Mechanica Sinica/Lixue Xuebao
Issue number1
Publication statusPublished - 1 Mar 2010


  • Articular cartilage
  • Inhomogeneous
  • Osmotic pressure
  • Triphasic model
  • Unaxial module

ASJC Scopus subject areas

  • Computational Mechanics
  • Mechanical Engineering

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