Abstract
1,4,13-Trihydroxy-eudesm-11(12)-ene, a new eudesmane derivative (3), (9E)-8,11,12-trihydroxyoctadecenoic acid methyl ester, a new fatty acid ester (2) and tianshic acid (1) were obtained from the stems of Sambucus williamsii. Their structures were elucidated by physiochemical properties and spectroscopic analysis. Both compounds 1 and 2 showed stimulating effects on alkaline phosphatase activity of the osteoblastic UMR106 cell about 1.5 fold at 30 μmol/l while they had no effects on cell proliferation.
Original language | English |
---|---|
Pages (from-to) | 676-678 |
Number of pages | 3 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 54 |
Issue number | 5 |
DOIs | |
Publication status | Published - 15 May 2006 |
Keywords
- Alkaline phosphatase activity
- Eudesmane
- Fatty acid
- Sambucus williamsii
- UMR106 cell
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry
- General Chemistry
- Pharmacology