A new eudesmane derivative and a new fatty acid ester from Sambucus williamsii

Xujuan Yang, Man Sau Wong, Naili Wang, Albert Sun Chi Chan, Xinsheng Yao

Research output: Journal article publicationJournal articleAcademic researchpeer-review

11 Citations (Scopus)

Abstract

1,4,13-Trihydroxy-eudesm-11(12)-ene, a new eudesmane derivative (3), (9E)-8,11,12-trihydroxyoctadecenoic acid methyl ester, a new fatty acid ester (2) and tianshic acid (1) were obtained from the stems of Sambucus williamsii. Their structures were elucidated by physiochemical properties and spectroscopic analysis. Both compounds 1 and 2 showed stimulating effects on alkaline phosphatase activity of the osteoblastic UMR106 cell about 1.5 fold at 30 μmol/l while they had no effects on cell proliferation.
Original languageEnglish
Pages (from-to)676-678
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume54
Issue number5
DOIs
Publication statusPublished - 15 May 2006

Keywords

  • Alkaline phosphatase activity
  • Eudesmane
  • Fatty acid
  • Sambucus williamsii
  • UMR106 cell

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Pharmacology

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