A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications

X. C. Li; Y. C. Seow; J. Wu; K. Xu; J. T. Lin; A. Q. Liu

A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications

X. C. Li, Y. C. Seow, J. Wu, K. Xu, J. T. Lin, A. Q. Liu

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

Abstract

This paper reports the measurement of refractive index (RI) of buffer solution using the evanescent wave (EW) based on liquid waveguide sensor using microflidic chip technique and employing the charge-coupled device (CCD) detection tecnique. The sample is injected into one cladding channel, and then the profile of the modal power distribution changes due to the change of RI, i.e. the intensity area, are used to determine the sample's RI. The sensitivity is 9 × 10^-5μm^-2. Moreover, the CCD detection technique is easy and real-time measuremnet. It is promising for cell biophysical, label-free detection and diagno applitions.

Original language	English
Pages	952-954
Number of pages	3
Publication status	Published - Oct 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 12 Oct 2008 → 16 Oct 2008

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	12/10/08 → 16/10/08

Keywords

Evanescent wave and refractive index
Liquid waveguide

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

@conference{bf8ca31a26514701b1760321b731a1af,

title = "A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications",

abstract = "This paper reports the measurement of refractive index (RI) of buffer solution using the evanescent wave (EW) based on liquid waveguide sensor using microflidic chip technique and employing the charge-coupled device (CCD) detection tecnique. The sample is injected into one cladding channel, and then the profile of the modal power distribution changes due to the change of RI, i.e. the intensity area, are used to determine the sample's RI. The sensitivity is 9 × 10-5μm-2. Moreover, the CCD detection technique is easy and real-time measuremnet. It is promising for cell biophysical, label-free detection and diagno applitions.",

keywords = "Evanescent wave and refractive index, Liquid waveguide",

author = "Li, {X. C.} and Seow, {Y. C.} and J. Wu and K. Xu and Lin, {J. T.} and Liu, {A. Q.}",

year = "2008",

month = oct,

language = "English",

pages = "952--954",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

}

Li, XC, Seow, YC, Wu, J, Xu, K, Lin, JT & Liu, AQ 2008, 'A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications', Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States, 12/10/08 - 16/10/08 pp. 952-954.

A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications. / Li, X. C.; Seow, Y. C.; Wu, J. et al.
2008. 952-954 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

TY - CONF

T1 - A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications

AU - Li, X. C.

AU - Seow, Y. C.

AU - Wu, J.

AU - Xu, K.

AU - Lin, J. T.

AU - Liu, A. Q.

PY - 2008/10

Y1 - 2008/10

N2 - This paper reports the measurement of refractive index (RI) of buffer solution using the evanescent wave (EW) based on liquid waveguide sensor using microflidic chip technique and employing the charge-coupled device (CCD) detection tecnique. The sample is injected into one cladding channel, and then the profile of the modal power distribution changes due to the change of RI, i.e. the intensity area, are used to determine the sample's RI. The sensitivity is 9 × 10-5μm-2. Moreover, the CCD detection technique is easy and real-time measuremnet. It is promising for cell biophysical, label-free detection and diagno applitions.

AB - This paper reports the measurement of refractive index (RI) of buffer solution using the evanescent wave (EW) based on liquid waveguide sensor using microflidic chip technique and employing the charge-coupled device (CCD) detection tecnique. The sample is injected into one cladding channel, and then the profile of the modal power distribution changes due to the change of RI, i.e. the intensity area, are used to determine the sample's RI. The sensitivity is 9 × 10-5μm-2. Moreover, the CCD detection technique is easy and real-time measuremnet. It is promising for cell biophysical, label-free detection and diagno applitions.

KW - Evanescent wave and refractive index

KW - Liquid waveguide

UR - http://www.scopus.com/inward/record.url?scp=84902481338&partnerID=8YFLogxK

M3 - Conference presentation (not published in journal/proceeding/book)

AN - SCOPUS:84902481338

SP - 952

EP - 954

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

A liquid-waveguide-based evanescent wave sensor for high sensitivity real time detection and label free biosensing applications

Abstract

Conference

Keywords

ASJC Scopus subject areas

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